Dexamethasone acts as a radiosensitizer in three astrocytoma cell lines via oxidative stress
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منابع مشابه
Dexamethasone acts as a radiosensitizer in three astrocytoma cell lines via oxidative stress
Glucocorticoids (GCs), which act on stress pathways, are well-established in the co-treatment of different kinds of tumors; however, the underlying mechanisms by which GCs act are not yet well elucidated. As such, this work investigates the role of glucocorticoids, specifically dexamethasone (DEXA), in the processes referred to as DNA damage and DNA damage response (DDR), establishing a new app...
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متن کاملThe in-vitro chemosensitivity of three cell lines derived from the VM/DK spontaneous murine astrocytoma.
Three cell lines, VM/Dk P497 P540 and P560 derived from the VM spontaneous murine astrocytoma have previously been fully characterised and found to differ in their degree of astrocytic differentiation. The in vitro chemosensitivity of the three lines has been investigated using the 35S-methionine uptake assay. Differential chemosensitivity was found to exist between the cell lines. The pattern ...
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ژورنال
عنوان ژورنال: Redox Biology
سال: 2015
ISSN: 2213-2317
DOI: 10.1016/j.redox.2015.06.006